Take a few drops and pat serum in over face. Use after cleansing and before moisturizing. Ensure the serum is fully absorbed before layering. Follow up with a moisturizer or Hyaluronic Acid Serum. To be used only at night. Usage Notes: Recommended for those over 25 years of age. Retinol is a potent active and hence we recommend introducing your skin to Retinol gradually. Start by using this serum once a week. Once your skin settles in, increase usage to twice a week and then subsequently on alternate nights. Remember to use an SPF on the following day. If your skin experiences some purging initially, dont worry this is the retinization period where your skin is gearing up to adapt and adjust. Retinol tends to react with sunlight leading to loss of efficacy. Hence ensure to store the amber bottle in a cool, dry place away from direct light.